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A-01: Integrated femtosecond laser technology for therapeutic application in corneal surgery

The goal of the project is to set up and conduct research into an ultraviolet femtosecond laser for corneal surgery. With this device, it should then be possible to correct defective vision in the human eye with much greater precision. The technical objective is to develop a laser system with an ultraviolet wavelength of 345 nm. The device will enable tissue ablation for the purpose of refractive correction, a procedure not possible with a sufficient degree of precision using existing methods.

A-06: Semi-synthetic corneal substrate for reconstructing and regenerating the surface of the eye


There is a large number of patients suffering from corneal diseases that lead to superficial wound healing impairment with opacity of the corneal epithelium and/or corneal stroma. There is a high demand for materials to cover such corneal surface defects. The objective of this experimental project is to develop various semi-synthetic biomatrices based on collagen for the individual treatment of various types of eye surface defects, and to conduct subsequent experimental and clinical trials.

A-04: Low-cost fundus camera for the Third World

The project "Low-cost Fundus Camera for the Third World" will research into and demonstrate technical possibilities for funduscopy with a telemedical connection, with a concrete, application-oriented perspective for use in developing countries. A demonstrator for optimized illumination and imaging optics for non-mydriatic representation of the fundus will be created for this purpose. If possible, a digital image scanner available on the mass market will be used to scan the fundus.

A-02: E-Atlas – barrier-free publication of medical images independent of any platform

The world's largest image database for ophthalmology, the "Atlas of Ophthalmology", is now available as an app for mobile devices. With just a single click, doctors, medicine students or laymen interested in health issues can receive over 6,000 clinical illness patterns on their iPhone. Doctors therefore always have decisive information at hand for visual diagnoses, confirmation of diagnoses or for informing the patient – a situation which clearly benefits the patient, whose care is improved by the eye app.

This iPhone application was developed within the framework of a funded project in the

A-05: Short pulse laser system for the treatment of age-related macular degeneration

Developing a laser procedure (frequency-doubled Nd:YAG solid-state lasers) for treating pathological changes in the retinal pigment epithelium in connection with age-related macula degeneration. For the first time ever, the product to be developed will provide a treatment option for the early form of age-related macula degeneration, which progressively leads to a loss of central vision and, with it, the ability to read. In Germany alone, a one-off market for up to 3,000,000 people can be expected for this indication.

The goal is to develop a system that has decisive advantages over existing

A-03: Implantable lens as an "eyeglass-replacing contact lens"

The objective here is to develop new technologies for treating presbyopia based on known technological results relating to phakic intraocular lenses. The research project is focusing on creating and utilizing new potential for the laser-aided manufacture of phakic IOLs. Existing processes for the manufacture of (phakic) IOLs are time consuming and cost-intensive. Laser-aided manufacturing should therefore be based on potentially giving the surface a microstructure to optimize production times and tool wear.

Project Duration

01.07.2010 - 31.12.2012

Project Partners

  • HumanOptics AG

A-07: Selective surface modification of intraocular lenses by means of ultrashort-pulsed laser radiation to reduce reflections

Project objective(s)

At the heart of the project is the idea of developing an IOL that can safely prevent the occurrence of negative dysphotopsia (ND).

ND is a post-surgery complication that occurs in up to 15% of patients following implantation of modern foldable lenses, e.g. in the treatment of cataracts. Patients with this complication complain of an irritating, blinder-like restriction of the visual field which is most likely caused by shadows. These shadows are attributed to edge glare phenomena.